Cancer Terms

TNFR1 Signaling Pathway

Cancer Terms -> Biochemical Pathway -> Signaling Pathways -> TNFR1 Signaling Pathway

TNFR1 Signaling Pathway Definition

TNFR1 (p55, CD120a) is the receptor for TNF-alpha and also will bind TNF-beta. Upon binding TNF-alpha a TNFR1+ cell is triggered to undergo apoptosis. This critical regulatory process is accomplished by activating the proteolytic caspase cascade that results in the degradation of many critical cellular proteins. (BioCarta)

TNFR1 Signaling Pathway Synonyms

TNFR1 Signaling Pathway

Terms in TNFR1 Signaling Pathway category



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