TPMT-1 Allele
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TPMT-1 Allele Definition
Human TPMT wild-type allele is located in the vicinity of 6p22.3 and is approximately 26 kb in length. This allele, which encodes thiopurine S-methyltransferase protein, is involved in the S-methylation of thiopurine drugs. Certain allelic variants of the TPMT gene are associated with either decreased gene expression or reduced enzymatic activity of their corresponding protein products.
TPMT-1 Allele Synonyms
TPMT wt Allele, TPMT Wild-type Allele, TPMT*1, TPMT*1 Allele, TPMT, Wild-type, Thiopurine S-Methyltransferase wt Allele
Terms in TPMT-1 Allele category
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