TYMS wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Transferase Gene -> Methyltransferase Gene -> TYMS Gene -> TYMS wt Allele

TYMS wt Allele Definition

Human TYMS wild-type allele is located in the vicinity of 18p11.32 and is approximately 16 kb in length. This allele, which encodes thymidylate synthase protein, is involved in maintenance of the thymidine-5'-monophosphate (dTMP) pool necessary for DNA replication and repair. Certain allelic variants of the TYMS gene confer resistance to chemotherapy.

TYMS wt Allele Synonyms

TYMS wt Allele, TMS, TS, Thymidylate Synthase wt Allele

Terms in TYMS wt Allele category

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