Cancer Terms

TYROBP wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> TYROBP Gene -> TYROBP wt Allele

TYROBP wt Allele Definition

Human TYROBP wild-type allele is located in the vicinity of 19q13.1 and is approximately 4 kb in length. This allele, which encodes TYRO protein tyrosine kinase-binding protein, plays a role in the modulation of killer cell activation. Mutation of the gene is associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy.

TYROBP wt Allele Synonyms

TYROBP wt Allele, DAP12, KARAP, PLO-SL, PLOSL, TYRO Protein Tyrosine Kinase Binding Protein wt Allele, TYROBP

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