Tetradecanoylphorbol Acetate
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Tetradecanoylphorbol Acetate Definition
A phorbol ester with potential antineoplastic effects. Tetradecanoylphorbol acetate (TPA) induces maturation and differentiation of hematopoietic cell lines, including leukemic cells. This agent may induce gene expression and protein kinase C (PKC) activity. In addition to potential antineoplastic effects, TPA may exhibit tumor promoting activity. (NCI04)
Tetradecanoylphorbol Acetate Synonyms
Tetradecanoylphorbol Acetate, 12-O-tetradecanoylphorbol-13-acetate, Lonomycin, PMA, PMAS, Phorbol Myristate Acetate, TPA
Terms in Tetradecanoylphorbol Acetate category
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