Therapeutic Vascular Endothelial Growth Factor
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Therapeutic Vascular Endothelial Growth Factor Definition
A recombinant therapeutic agent which is chemically identical to or similar to endogenous vascular endothelial growth factor (VEGF). Produced by a wide variety of cell types, endogenous VEGF is a homodimeric, glycosylated protein that is a highly specific mitogen for vascular endothelial cells; significantly influences vascular permeability; appears to play a role in neovascularisation under physiological conditions; is a potent chemoattractant; has pro-coagulatory activities; and is hypoxia-inducible. Therapeutic VEGF may be used to induce angiogenesis in the treatment of ischemic conditions and may have a role in stimulating nerve regeneration. (NCI04)
Therapeutic Vascular Endothelial Growth Factor Synonyms
Recombinant Vascular Endothelial Growth Factor, VEGF, VPF, Vascular Endothelial Growth Factor, Vascular Permeability Factor, rhuVEGF, vascular endothelial growth factor
Terms in Therapeutic Vascular Endothelial Growth Factor category
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