Trastuzumab
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Trastuzumab Definition
A recombinant humanized monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). After binding to HER2 on the tumor cell surface, trastuzumab induces an antibody-dependent cell-mediated cytotoxicity against tumor cells that overexpress HER2. HER2 is overexpressed by many adenocarcinomas, particularly breast adenocarcinomas. (NCI04)
Trastuzumab Synonyms
Trastuzumab, Anti-ERB-2, Anti-HER2/c-erbB2 Monoclonal Antibody, Anti-c-ERB-2, Anti-c-erbB2 Monoclonal Antibody, Anti-erbB-2, Anti-erbB2 Monoclonal Antibody, Anti-p185-HER2, HER2 Monoclonal Antibody, Herceptin, MoAb HER2, Monoclonal Antibody HER2, Monoclonal Antibody c-erb-2, TRASTUZUMAB, c-erb-2 Monoclonal Antibody, rhuMAb HER2, trastuzumab
Terms in Trastuzumab category
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