Triapine
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Triapine Definition
A synthetic heterocyclic carboxaldehyde thiosemicarbazone with potential antineoplastic activity. Triapine inhibits the enzyme ribonucleotide reductase, resulting in the inhibition of the conversion of ribonucleoside diphosphates to deoxyribonucleotides necessary for DNA synthesis. This agent has been shown to inhibit tumor growth in vitro. (NCI04)
Triapine Synonyms
Triapine, 3-AP, 3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone, 3-Apct, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, OCX-191
Terms in Triapine category
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