Cancer Terms

Upstream Stimulatory Factor 2

Cancer Terms -> Gene Product -> Protein -> Protein Complex Subunit -> Upstream Stimulatory Factor 2

Upstream Stimulatory Factor 2 Definition

Ubiquitously expressed as 3 alternative isoforms by human USF2 Gene, nuclear Upstream Stimulatory Factor 2 is a bHLH transcription factor involved in transcription of a variety of cellular genes that binds to symmetrical E-box DNA (CACGTG) in viral and cellular promoters as a homodimer or USF1/USF2 heterodimer (USF). Efficient DNA binding requires dimerization with another bHLH protein. USF1/USF2A heterodimer represents most USF binding activity. (NCI)

Upstream Stimulatory Factor 2 Synonyms

Upstream Stimulatory Factor 2, FIP, FOS-Interacting Protein, Major Late Transcription Factor 2, USF2, Upstream Transcription Factor 2

Terms in Upstream Stimulatory Factor 2 category



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