Vitamin A Acid

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Cell Differentiating Agent -> Differentiation Inducer -> Retinoic Acid Agent -> Vitamin A Acid

Vitamin A Acid Definition

A naturally-occurring acid of retinol. Tretinoin binds to and activates retinoic acid receptors (RARs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, and inhibition of tumorigenesis. This agent also inhibits telomerase, resulting in telomere shortening and eventual apoptosis of some tumor cell types. The oral form of tretinoin has teratogenic and embryotoxic properties.

Vitamin A Acid Synonyms

Tretinoin, (All-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid, 2,4,6,8-Nonatetraenoic acid, 3, 7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-, ATRA, Aberel, Airol, Aknoten, All-trans Retinoic Acid, All-trans Vitamin A Acid, Avita, Cordes Vas, Dermairol, Epi-Aberel, Eudyna, Renova, Retin-A, Retin-A MICRO, Retinoic Acid, Retisol-A, Ro 5488, Stieva-A, Stieva-A Forte, TRETINOIN, Trans Retinoic Acid, Trans Vitamin A Acid, Tretinoinum, Vesanoid, Vitamin A Acid, Vitamin A acid, Vitamin A acid, all-trans-, Vitinoin, all trans-Retinoic acid, all-trans-Retinoic acid, all-trans-Vitamin A acid, beta-Retinoic Acid, trans-Retinoic Acid, trans-Retinoic acid, tretinoin

Terms in Vitamin A Acid category

Tretinoin Liposome