Cancer Terms

WNT2B Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Signaling Protein -> WNT Family Protein -> WNT2B Protein

WNT2B Protein Definition

Encoded by human oncogene WNT2B Gene (WNT Family), the novel 391-amino acid 43.8 kD (precursor) WNT2B Protein is a homolog of Xenopus Xwnt2 and expressed in fetal brain, lung, and kidney, as well as in a variety of adult tissues. Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine, and colon. Isoform 2 is expressed in fetal brain, lung, and kidney, and in adult brain and testis. Highly-conserved, 350-400 amino acid WNT glycoproteins constitute cysteine-rich, short-range ligands for frizzled family seven transmembrane receptors involved in embryonic cell fate determination and patterning, as well as cell growth or differentiation in some adult mammalian tissues. (NCI)

WNT2B Protein Synonyms

WNT2B Protein, WNT-2B Protein, WNT13 Protein, WNT2B, Wingless-Type MMTV Integration Site Family Member 2B Protein, XWNT2 Protein

Terms in WNT2B Protein category



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