Cancer Terms

WRN wt Allele

Cancer Terms -> Gene -> Enzyme Gene -> Hydrolase Gene -> Helicase Gene -> WRN Gene -> WRN wt Allele

WRN wt Allele Definition

Human WRN wild-type allele is located within 8p12-p11.2 and is approximately 140 kb in length. This allele, which encodes Werner syndrome ATP-dependent helicase protein, is involved in the both the formation of DNA replication focal centers and the unwinding of single- and double-stranded DNA in a 3'-5' direction. Certain allelic variants of this gene cause Werner syndrome.

WRN wt Allele Synonyms

WRN wt Allele, RECQ3, RECQL2, RECQL3, Werner Syndrome wt Allele

Terms in WRN wt Allele category



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