WRN wt Allele
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WRN wt Allele Definition
Human WRN wild-type allele is located within 8p12-p11.2 and is approximately 140 kb in length. This allele, which encodes Werner syndrome ATP-dependent helicase protein, is involved in the both the formation of DNA replication focal centers and the unwinding of single- and double-stranded DNA in a 3'-5' direction. Certain allelic variants of this gene cause Werner syndrome.
WRN wt Allele Synonyms
WRN wt Allele, RECQ3, RECQL2, RECQL3, Werner Syndrome wt Allele
Terms in WRN wt Allele category
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