mTOR Inhibitor

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Enzyme Inhibitor -> Protein Kinase Inhibitor -> mTOR Inhibitor

mTOR Inhibitor Definition

Any agents that inhibit mTOR (FK506 binding protein 12-rapamycin associated protein 1), one of the protein kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. mTOR acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.

mTOR Inhibitor Synonyms

mTOR Inhibitor

Terms in mTOR Inhibitor category

AP23573
CCI-779
Nanoparticle Albumin-Bound Rapamycin
Zotarolimus
mTOR Kinase Inhibitor AZD8055
mTOR Kinase Inhibitor OSI-027