Cullin Family Protein

Cancer Terms -> Gene Product -> Protein -> Protein Organized by Function -> Regulatory Protein -> Cullin Family Protein

Cullin Family Protein Definition

Encoded by Cullin Family Genes, Cullin Family Proteins are components of SCF ubiquitin ligase complexes or E3 ubiquitin ligase complexes with elongin BC complexes and other factors, involved in ubiquitination and proteasomal degradation of target cell cycle, signal transduction, and transcription proteins. Cullins may act in these multisubunit complexes as a scaffold for substrates and ubiquitin-conjugating enzymes and interact with RBX1, RNF7, CYCE, and/or TIP120A/CAND1. (NCI)

Cullin Family Protein Synonyms

Terms in Cullin Family Protein category

Cullin-1 Protein
Cullin-2 Protein
Cullin-3 Protein
Cullin-4A Protein
Cullin-5 Protein