Cancer Terms

GEM 231

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Agent -> Antisense Agent -> Mixed-Backbone Oligonucleotide -> GEM 231

GEM 231 Definition

A mixed backbone oligonucleotide exhibiting antitumor activity. GEM-231 is complementary to the RI alpha subunit of Protein Kinase A (PKA), resulting in downregulation of PKA expression and ultimately tumor growth. (NCI)

GEM 231 Synonyms

GEM 231, GEM231, Gene Expression Modulator 231

Terms in GEM 231 category



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