Cancer Terms

Penicillamine

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Antineoplastic Agent -> Angiogenesis Inhibitor -> Angiogenesis Activator Inhibitor -> Penicillamine

Penicillamine Definition

A beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and increases their urinary excretion. Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. (NCI04)

Penicillamine Synonyms

Penicillamine, .beta.,.beta.-Dimethylcysteine, 3-Mercapto-D-valine, Alpha-amino-beta-methyl-beta-mercaptobutyric Acid, Atamir, Beta,Beta-dimethylcysteine, Beta-thiovaline, Cuprenil, Cuprimine, Cupripen, D-Mercaptovaline, D-Penicillamine, Depamine, Depen, Distamine, Kelatin, Mercaptyl, Metalcaptase, PENICILLAMINE, Pendramine, Perdolat, Sufortan, Trolovol, penicillamine

Terms in Penicillamine category



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