SU6668
Cancer Terms ->
Drugs and Chemicals ->
Pharmacologic Substance ->
Antineoplastic Agent ->
Angiogenesis Inhibitor ->
Angiogenesis Activator Inhibitor -> SU6668
SU6668 Definition
An orally bioavailable receptor tyrosine kinase inhibitor. SU6668 binds to and inhibits the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), thereby inhibiting angiogenesis and cell proliferation. SU6668 also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. (NCI04)
SU6668 Synonyms
SU6668, SU 6668, Sugen SU6668
Terms in SU6668 category
Copyright © Cancer Terms 2014 All rights reserved. | Terms of Use | Low Carb Foods
No reproduction or republication permitted.