TNFRSF11B wt Allele

Cancer Terms -> Gene -> Ligand Binding Protein Gene -> Receptor Gene -> Cytokine Receptor Gene -> TNF Receptor Family Gene -> TNFRSF11B Gene -> TNFRSF11B wt Allele

TNFRSF11B wt Allele Definition

Human TNFRSF11B wild-type allele is located in the vicinity of 8q24 and is approximately 29 kb in length. This allele, which encodes tumor necrosis factor receptor superfamily member 11B protein, plays a role in bone homeostasis through the mediation of osteoclast apoptosis. Deletions and mutations in the gene are associated with juvenile Paget disease of the bone.

TNFRSF11B wt Allele Synonyms

TNFRSF11B wt Allele, MGC29565, OCIF, OPG, TR1, Tumor Necrosis Factor Receptor Superfamily, Member 11B (Osteoprotegerin) wt Allele

Terms in TNFRSF11B wt Allele category

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