Therapeutic Transforming Growth Factor

Cancer Terms -> Drugs and Chemicals -> Pharmacologic Substance -> Biological Agent -> Therapeutic Growth Factor -> Therapeutic Transforming Growth Factor

Therapeutic Transforming Growth Factor Definition

A recombinant therapeutic agent which is chemically identical to or similar to endogenous transforming growth factor (TGF). Representing peptides of two distinct classes, designated TGF-alpha and TGF-beta, TGFs are produced by various non-transformed cells during the development of mammalian embryos and are found in urine and plasma; TGFs are also produced by some human carcinomas and cell lines transformed by viral and cellular oncogenes. TGFs affect bone formation and remodeling by inhibition of the synthesis of collagen and release of calcium. (NCI04)

Therapeutic Transforming Growth Factor Synonyms

Recombinant Transforming Growth Factor, TGF, Transforming Growth Factor, Tumor Growth Factors

Terms in Therapeutic Transforming Growth Factor category

Therapeutic Transforming Growth Factor-Alpha
Therapeutic Transforming Growth Factor-Beta